Biden, 78, told Americans "there's nothing to worry about" when he got his first dose of the Pfizer-BioNTech vaccine at the Christiana Hospital in Newark, Delaware, on Dec 21.
His team said that his second jab would also be done in front of the media, without giving further details.
More than 374,000 people have died from COVID-19 in America, and Biden on Friday slammed the troubled distribution of vaccines by President Donald Trump's administration as a "travesty".
About 6.7 million Americans have so far received their first shot - far short of the target of 20 million by the end of 2020.
Biden, who will be inaugurated on Jan 20, plans to release every available dose of the vaccines, rather than holding back half to make sure people receive their booster shots on time as is the current protocol.
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